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Digitale Medien

Phagocytic cells metabolize 25-hydroxyvitamin D"3 to 10-oxo-19-nor-25-hydroxyvitamin D"3 and a new metabolite, 8α,25-dihydroxy-9, 10-seco-4,6,10(19)-cholestatrien-3-one

Hayashi, T. ; Yamada, S. ; Miyaura, C. ; [weitere]

Amsterdam : Elsevier

FEBS Letters 218 (1987), S. 200-204

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Details

ISSN: 0014-5793

Schlagwort(e): 10-Oxo-19-nor-25-hydroxyvitamin D"3 ; 8α,25-Dihydroxy-9,10-seco-4,6,10(19)-cholestatrien-3-one ; Macrophage ; Phagocytic cell ; Vitamin D metabolism

Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Thema: Biologie , Chemie und Pharmazie , Physik

Materialart: Digitale Medien

URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(87)81046-3

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Digitale Medien

Distribution of concanavalin A binding sites on normal human urinary bladder mucosa and bladder tumors by transmission and scanning electron microscopy and x-ray microanalysis (1984)

Takayama, H.

Springer

Urological research 12 (1984), S. 135-141

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ISSN: 1434-0879

Schlagwort(e): Concanavalin A ; Lectin receptors ; Bladder tumor ; Electron microscopy ; X-ray microanalysis

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary We used concanavalin A (con A)-peroxidase-iron dextran-diaminobenzidine (DAB) technique for the electron microscopic detection of con A binding sites on cell membranes. Normal bladder mucosa showed a sparse distribution of con A binding sites with both transmission (TEM) and scanning (SEM) electron microscopy, but bladder tumors showed a higher concentration in the distribution of con A binding sites in proportion to the histopathological grade of transitional cell carcinoma. Quantitative estimation of the con A binding sites was attempted using scanning X-ray pulse analysis of iron elements contained in the reaction complexes. Con A binding sites were quantitatively the smallest in normal mucosa, increasing proportionate to the grade of the bladder tumor. Some specimens were compared by the ferritin-labelled method and the pattern of ferritin conjugates distribution was similar to that seen with the con A-peroxidase-iron dextran method.