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  • 1
    Electronic Resource
    Electronic Resource
    The new neuropathology of degenerative frontotemporal dementias (1996)
    Springer
    Acta neuropathologica 91 (1996), S. 127-134 
    Details
    ISSN: 1432-0533
    Keywords: Key words Frontal lobe dementia ; Alzheimer's ; disease ; Pick's disease ; Corticobasal degeneration ; Motor neuron disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The clinical features and recent developments in the neuropathology of frontotemporal dementia are reviewed. The five main neurodegenerative disorders that underlie the clinical syndrome of frontotemporal dementia are distinguished using immunohistochemistry with antisera to ubiquitin and tau proteins. Motor neuron disease-type dementia is characterised by ubiquitin-immunoreactive intraneuronal inclusions in cortical layer II and the hippocampal dentate granule cells. A diagnosis of Alzheimer's disease changes is based upon the presence of neurofibrillary tangles, which immunostain with antibodies to tau and ubiquitin, and many associated neuritic plaques. Corticobasal degeneration is diagnosed by the presence of tau-immunoreactive, but ubiquitin-non-reactive intraneuronal inclusions in cortical layer II and the substantia nigra. Pick's disease is restricted to cases with tau- and ubiquitin-immunoreactive spherical cortical intraneuronal inclusions (Pick bodies), best seen in the hippocampal dentate gyrus and frontotemporal cortex. Dementia of frontal type is the preferred term for cases in which no intraneuronal inclusions are seen with antisera to tau and ubiquitin. A practical approach to the pathological diagnosis of frontotemporal dementia and the differential diagnosis of the five disorders using immunohistochemical studies is provided.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010050403
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of holmium laser radiation on stress, temperature and structure of cartilage (1998)
    Springer
    Lasers in medical science 13 (1998), S. 73-77 
    Details
    ISSN: 1435-604X
    Keywords: Cartilage ; Chondrocyte ; Laser ; Stress relaxation ; Structure alterations ; Thermal and mechanical effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract It is difficult to permanently alter the shape of cartilage in a controlled way. In otolaryngology and plastic surgery several procedures are done to alter the shape of cartilage, for example the correction of a deviated nasal septum and surgery for bat ears. The aim of this paper is to study the main parameters which are necessary for the phenomenon of reshaping of cartilage under non-destructive laser radiation. We have measured temperature and stress in cartilage when it is being reshaped with a holmium laser, It has been shown that laser-induced stress relaxation in cartilage takes place when the tissue temperature exceeds 70°C. We have determined the conditions which allow the shape of cartilage to be altered without producing any pronounced alteration to matrix structure or chondrocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00592962
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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