ISSN:
1432-1106
Schlagwort(e):
Neurogenesis
;
Dentate granule cells
;
Tritiated thymidine (3H-Tdr)
;
Adult
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Summary Nine-month-old rats were injected with 5 μCi 3H-thymidine (3H-Tdr) and allowed to survive for 20 days. In light-microscopic radioautographs, labeled cells were found in the granule cell layer of the hippocampus. Analysis of electron micrographs of the labeled cells, taken from re-embedded 1.5 μm radioautographic sections, clearly demonstrated their neuronal nature with synapses along their cell bodies and dendrites. Our results indicate that 0.025% of the granule neurons are heavily labeled in the dorsal hippocampus. Electron microscopy of re-embedded light-microscopic radioautographic sections confirms that granule neurons in the rodent are newly formed up until 9 months after birth.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00237141
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