ISSN:
1432-2072
Keywords:
Depression
;
Serotonin
;
Metabolism
;
Serotonin Precursors
;
Clomipramine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract In some depressive patients, regarded as therapy-resistant, the antidepressive effect of 1-5-hydroxytryptophan (in combination with a peripheral decarboxylase inhibitor) was ehanced by clomipramine at a dosage which, as such, was suboptimal. This probably means that the therapeutic effect of 1-5-hydroxy-tryptophan is based on increase of serotonin at central serotonin receptors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00421379
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