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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 20 (1992), S. 281-284 
    ISSN: 1434-0879
    Keywords: Prostate fluid ; Testosterone ; Dihydrotestosterone ; Zinc ; Benign prostatic hyperplasia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In an attempt to determine whether the androgen profiles of the prostate fluid (EPS) mirror the concentrations in the prostate tissue, we have measured testosterone and dihydrotestosterone (DHT) in EPS and correlated their levels to the concentrations found in hyperplastic prostate tissue (BPH) obtained from the same 19 patients. Although androgen concentrations in EPS were very high (testosterone=106.7±81.9 ng/g dry weight; DHT=54.2±11.2 ng/g dry weight), they did not reflect the concentrations measured in BPH tissue (testosterone=7.56±1.54 ng/g dry weight; DHT=10.54±0.63 ng/g dry weight). Additionally the accumulation of tissular DHT usually associated with BPH was not mirrored in the EPS specimens which demonstrated a relatively higher concentration of testosterone when compared to DHT. In EPS, there was also a very strong correlation between testosterone and DHT concentrations (r=0.89; P〈0.01). We have also measured zinc concentrations in EPS and BPH tissue but were unable to detect any relationship between the two parameters. Significantly, however, EPS zinc concentrations showed a close correlation with EPS testosterone (r=0.73; P〈0.01) and DHT (r=0.69; P〈0.01) concentrations.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 69 (1994), S. 550-556 
    ISSN: 1439-6327
    Keywords: Muscle ; Metabolism ; Enzymes ; Buffer value
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The degree to which the y-intercept (Y-int) of the linear regression of maximal work output on exercise duration represented anaerobic capacity was determined in ten well-trained male cyclists [peak oxygen uptake ( $$\dot V{\text{O}}_{{\text{2peak}}} $$ = 69.8 (SD 4.2) ml · kg −1 · min −1). Each cyclist performed three exhausting cycle sessions on separate occasions; the mean exercise durations were 312, 243 and 141 s for the low (approximately 104% $$\dot V{\text{O}}_{{\text{2peak}}} $$ , medium (approximately 108% $$\dot V{\text{O}}_{{\text{2peak}}} $$ and high (approximately 113% $$\dot V{\text{O}}_{{\text{2peak}}} $$ intensities respectively, and Y-int (kilojoules; joules per kilogram was derived from the regression of work output on exercise duration. The muscle anaerobic adenosine 5′-triphosphate (ATP) yield (ΣATP) and anaerobic capacity (AC) were estimated from changes in metabolites in the vastus lateralis muscle and blood lactate concentration during the high intensity cycling session. The activities of glycogen phosphorylase, phosphofructokinase and citrate synthase, as well as muscle buffer value (in vitro β) were also determined. The Y-int (kilojoules) was positively correlated (P≤0.05) with AC (r=0.73), ΣATP (r=0.70) and in vitro β (r=0.71); similar correlations (P≤0.05) were observed for Y-int (joules per kilogram). The Y-int was not correlated (P〉0.05) with any enzyme activity. When the Y-int was transformed into oxygen equivalents [litres of oxygen equivalent (1 O2 Eq)] it was, on average, 0.92 1 O2 Eq lower than AC (P≤0.05); however, an alternative method of establishing the work-duration regression yielded a mean Y-int which was only 0.19 1 O2 Eq less than AC (P≥0.05). These findings support the validity of Y-int as a work estimate of anaerobic capacity in well-trained cyclists.
    Type of Medium: Electronic Resource
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