ISSN:
1434-193X
Keywords:
Nucleoside analogue
;
Nucleosides
;
Palladium
;
Dihydroxylations
;
Catalysts
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A convenient diastereoselective synthesis of an immediate precursor for a rapid access to a variety of homo-carbocyclic nucleosides, is described. The synthetic scheme involves a high yielding new type of Pd(0) catalyzed cyclization of a suitable hydrazine derivative together with a stereospecific OsO4 triggered dihydroxylation step.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
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