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  • 1980-1984  (2)
  • Distal tubule  (1)
  • Renal vascular organization  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Stimulation by human calcitonin of electrolyte transport in distal tubules of rat kidney (1983)
    Springer
    Pflügers Archiv 399 (1983), S. 111-118 
    Details
    ISSN: 1432-2013
    Keywords: Calcitonin ; Distal tubule ; Micropuncture ; Electron-probe ; Brattleboro rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of human calcitonin (HCT) on the distal tubule were investigated by micropuncture in hormone-deprived rats, i.e. in the absence of parathyroid hormone, antidiuretic hormone and glucagon, which might have masked these effects. Two groups of rats were studied: hormone-deprived and hormone-deprived+HCT, infused at 1.0 mU/min\100 g b.w. In the urine, HCT markedly reduced Ca and Mg excretion whereas excretion of water, Na and K was not significantly affected. Along the distal tubule, HCT strongly enhanced Na, Cl, Mg, Ca and total solute reabsorption, decreased K secretion but did not alter water or phosphate transport. It is concluded that HCT stimulated Na, Cl, Ca and Mg reabsorption. If, as suggested, HCT also stimulated the reabsorptive component of K transport, the hormone should therefore elicit the same physiological effects in the distal tubule and the thick ascending limb.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00663905
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Renal function and concentrating ability in a desert rodent: The gundi(Ctenodactylus vali) (1981)
    Springer
    Pflügers Archiv 390 (1981), S. 138-144 
    Details
    ISSN: 1432-2013
    Keywords: Desert rodents ; Renal concentrating ability ; Medullary recycling of urea ; Renal vascular organization ; Structure-function relationship
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Clearance and cortical micropuncture experiments were carried out on non diuretic gundis. In this species, the kidney has a long and well developed papilla but, unlike other desert rodents, the vascular organization of the outer medulla is very simple. After withdrawal of water supply for either 24 h or 3 days before the experiments, the urine osmolality was only 1,361±57,n=9, before and 1,136±89 mosmol ·kg−1 during anesthesia. The GFR per 100 g B. W. (0.450 ml ·min−1) is lower than in the rat studied under similar conditions. With regard to electrolytes the tubular handling of Na, Ca, K and Mg is similar to that observed for another desert rodent, psammomys obesus. For P, massive reabsorption (more than 30% of the filtered load) takes place along the distal convoluted tubule. The relatively poor concentrating ability of the gundi's kidney is not due to a lack of medullary recycling of urea since a net addition of urea to short loops of Henle is observed in this species. Physiological and morphological observations concerning the gundi and other desert rodent species suggest that the vascular bundle development in the outer medulla might affect the renal response to water deprivation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00590196
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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