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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Basic research in cardiology 92 (1997), S. 45-51 
    ISSN: 1435-1803
    Keywords: Dog ; Vineberg procedure ; coronary artery disease ; coronary bypass surgery ; myocardial ischemia ; transmyocardial laser revascularization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The concept of direct myocardial revascularization, achieving myocardial perfusion through means other than the normal coronary vasculature, has a long history with the most widely investigated technique being the Vineberg procedure; current interest centers around the encouraging preliminary clinical results obtained with transmyocardial laser revascularization. Despite significant previous research, the acute blood flow potential through the direct myocardial route remains unknown. Nontransmural laser channels were made in the distal LAD territory from the epicardial surface of 5 mongrel dogs to which an internal mammary artery was connected. A flow probe was placed on the distal most portion of the artery and an intercostal branch was cannulated for infusion of colored microspheres. Measurements were taken under baselin conditions and following LAD and epicardial collateral ligation. Under all conditions, blood flow pattern was of a to-and-fronature. At baseline, there was an average 0.60±0.24 ml/min net flow into the myocardium which was all contained within 0.5 cm of the central channel with a final myocardial perfusion of 0.011±0.016 ml/min/g. Following induction of ischemia average flow increased to 1.41±0.51 ml/min which extended as far as 1 cm from the channel with a final myocardial perfusion of 0.22±0.19 ml/min/g. In conclusion, a limited amount of acute myocardial perfusion can be achieved by the present technique of direct myocardial revascularization and the amount of flow is highly dependent upon the amount of flow through the native circulation.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-1561
    Keywords: Pest control agent ; plant extract ; Trewia nudiflora ; trewiasine ; control agent ; antifeedant ; morphogenic agent
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract An ethanol extract ofTrewia nudiflora (Euphorbiaceae) seed was tested as an agent for controlling several economically important insects. Results suggest that this plant extract acts as an antifeedant for the spotted cucumber beetle (Diabrotica undecimpunctata howardi Barber) and the European corn borer [Ostrinia nubilalis (Hübner)] but not for the other insects tested. Also indicated were morphogenic effects on the codlingmoth [Laspeyresia pomonella (L.)], disruption of the normal life cycle of the redbanded leafroller [Argyrotaenia velutinana (Walker)], and reduction in the progeny of the plum curculio [Conotrachelus nenuphar (Herbst)]. In addition, the extract was toxic to the striped cucumber beetle [Acalymma vittatum (F.)] and gave 100% control of the chicken body louse [Menacanthus stramineus (Nitzsch)] from 5 to 28 days. Fractionation of the extract was monitored by a bioassay usingO. nubilalis. This fractionation yielded six pure compounds, the most abundant of which was trewiasine. Its LD50 was 7.4 ppm when incorporated into the diet ofO. nubilalis. Dose-mortality relationships for the other compounds withO. nubilalis are presented.
    Type of Medium: Electronic Resource
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