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Digitale Medien

Pharmacological distinctions between “active” and “passive” avoidance memory formation as shown by manipulation of biogenic amine active compounds (1974)

Allen, C. ; Allen, Blair S. ; Rake, A. V.

Springer

Psychopharmacology 34 (1974), S. 1-10

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Details

ISSN: 1432-2072

Schlagwort(e): Memory ; Mice ; Reserpine ; Dopa ; 5HTP ; Indole Amines ; Catecholamines ; Active Avoidance ; Passive Avoidance

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Female CF-1 mice were trained either in a passive step-through avoidance or in an active one-way escape avoidance task. The apparent memory for either task (measured 8 days later) was reduced by reserpine dosage immediately after training. Five-hydroxytryptophane, given along with the reserpine, eliminated memory reduction for the passive training; Dopa, given along with the reserpine, did not eliminate memory deficit for the passive training. Five-hydroxytryptophane given along with reserpine did not eliminate the memory deficit for the active training; Dopa given along with the reserpine did eliminate memory reduction for the active training. Implications are discussed.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00421215

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