Electronic Resource
Springer
Journal of neurology
247 (2000), S. II58
ISSN:
1432-1459
Keywords:
Key Words Apoptosis
;
Cytokines
;
Dopamine neuron
;
Substantia nigra
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Parkinson’s disease is a neurodegenerative disease characterised by a massive loss of dopaminergic neurons in the substantia nigra. Yet glial cells may also participate in the pathophysiology of the disease. Indeed, glial cells can produce trophic factors which may stimulate neuronal survival or, alternatively, they could produce toxic compounds which may be involved in neuronal degeneration. This paper reviews the potentially protective or deleterious effects of glial cells in the substantia nigra of patients with Parkinson’s disease.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/PL00007762
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