ISSN:
1619-7089
Keywords:
Dosimetry
;
Iodine-123
;
Receptors
;
Benzodiazepine
;
Flumazenil
;
Iomazenil
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The distribution of the central benzodiazepine receptor specific ligand iodine-123 iomazenil was investigated in seven human adults from whole-body scans, blood samples and urine collected up to 24 h after injection. Using 12 source organs, the MIRD method was applied to calculate the absorbed radiation dose of the radioligand in various organs. The urinary bladder wall (0.15 mGy/MBq), lower large intestinal wall (0.071 mGy/MBq) testes (0.044 mGy/MBq) and upper large intestined wall (0.038 mGy/MBq) received the highest absorbed doses. The average effective dose equivalent of 123I-IBZM for adults was estimated to be 0.033 mSv/MBq.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00176551
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