ISSN:
1432-0533
Keywords:
Juvenile parkinsonism
;
Substantia nigra
;
Central pale area
;
Early Lewy body
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Neurons containing a central pale area which may possibly represent an early cytoplasmic change before Lewy body maturation were observed in the substantia nigra from a rare autopsy case of juvenile parkinsonism. Ultrastructurally, such neurons exhibited cytoplasmic swelling along with disappearance of the rough endoplasmic reticulum from the central part of the perikaryon. The pale central cytoplasm was replaced by numerous-cored vesicles, mitochondria, ribosomelike granules and a few Lewy body filaments. The relation of this central pale area to the pale body is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00334457
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