ISSN:
1432-0878
Keywords:
Ventricle
;
Tanycytes
;
Monoamine transport
;
Autoradiography
;
Electron microscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary This investigation has dealt with a light and electron microscopic autoradiographic analysis of the median eminence of the rat following intraventricular infusion of 3H-dopamine. This study has demonstrated that 3H-dopamine, once infused into the mammalian cerebral ventricular system, is rapidly and selectively absorbed by tanycytes and transported to the contact zone within 5 minutes after ventricular infusion. Certain axon terminals in the ependymal, hypendymal, and palisade-contact zones selectively sequester 3H-dopamine as do subpopulations of arcuate neurons. This picture of intense labelling of neurons and axon terminals is discussed with respect to monoaminergic re-uptake mechanisms. Uptake and transport of 3H-DA by tanycytes is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00221067
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