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  • 1
    Electronic Resource
    Electronic Resource
    A quantitative and ultrastructural study of substantia nigra and nucleus centralis superior in Alzheimer's disease (1985)
    Springer
    Acta neuropathologica 68 (1985), S. 218-223 
    Details
    ISSN: 1432-0533
    Keywords: Alzheimer's disease ; Electron microscopy ; Substantia nigra ; Nucleus centralis superior
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In four patients with presenile Alzheimer's disease (AD) and three age-matched controls a quantitative study of neurons and neurofibrillary tangles (NFT) in the substantia nigra (SN) and nucleus centralis superior (NCS) was performed. A significant neuronal loss, similar in both nuclei, was found in AD cases, while the incidence of NFT was remarkably higher in NCS. Moreover, no significant correlation between neuronal loss and number of NFT was detected. An electron-microscopic study revealed that the subcortical NFT in NCS are made up of paired helical filaments in spite of their globose round shape.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00690198
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Italian multicenter study of dementia: a pathologically verified case of Alzheimer disease (1986)
    Springer
    Neurological sciences 7 (1986), S. 161-163 
    Details
    ISSN: 1590-3478
    Keywords: Alzheimer disease ; Electron microscopy ; Epidemiological study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Viene descritto lo studio neuropatologico di un caso incluso nello Studio Multicentrico Italiano sulla Demenza sulla base di dati clinici. L'esame istologico ed ultrastrutturale conferma la diagnosi di malattia di Alzheimer avvalorando quindi il protocollo clinico.
    Notes: Abstract The pathological findings in a case included in the Italian multicenter study of dementia on clinical grounds are reported. The histological and ultrastructural examination confirms the diagnosis of Alzheimer disease, evidence for the validity of the clinical protocol.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02230435
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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