ISSN:
1434-4726
Keywords:
Endocochlear potential
;
Vascular perfusion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A method is described for maintaining the cochlear potentials of the guinea pig via arterial perfusion of the surviving inner ear with an artificial medium devoid of oxygen carriers or oncotic agents. The endocochlear potential (EP) can be maintained at a normal level for periods in excess of 5 h; the responses of the EP to anoxia and to furosemide closely approximate those seen in the intact animal. This preparation may represent a simplified method for carrying out selected arterial perfusion experiments in the surviving inner ear.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00464250
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