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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 1070 (1991), S. 332-342 
    ISSN: 0005-2736
    Keywords: ATP ; Barnacle fiber ; Microinjection ; Sodium ion efflux
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 1106 (1992), S. 297-302 
    ISSN: 0005-2736
    Keywords: (Barnacle muscle fiber) ; Microinjection ; Ouabain-poisoned fiber ; Sodium ion efflux ; d-Inositol 1,4,5-triphosphate
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 123 (1997), S. 527-529 
    ISSN: 1432-1335
    Keywords: Nuclear protein tyrosine kinase ; Hepatocarcinogensis ; Isozyme
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The activity changes of isozymes of nuclear protein tyrosine kinase (nPTK) during chemically induced hepatocarcinogenesis in rats was studied. Two isozymes were isolated from rat liver by using ion exchange chromatography. These two isozymes were designated as nPTK-I and nPTK-II, and were found to be minor and major components of total nPTK respectively. These proved to be two different enzymes due to their different characteristics, such as molecular weights, electrical charges and kinetics. The specific activity nPTK-I and its percentages in total nPTK significantly increased in preneoplastic stage (week 10) and slightly elevated further in neoplastic stage (week 18). The specific activity of the nPTK-II moderately increased at week 10, but compared to its value at week 10, it decrease at week 18, resulted in gradual decrease of its percentage in total nPTK. These results indicate that rat hepatic nPTK-I and nTPK-II may be related to neoplastic and preneoplastic stages of rat liver respectively.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 123 (1997), S. 527-529 
    ISSN: 1432-1335
    Keywords: Key words Nuclear protein tyrosine kinase ; Hepatocarcinogensis ; Isozyme
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The activity changes of isozymes of nuclear protein tyrosine kinase (nPTK) during chemically induced hepatocarcinogenesis in rats was studied. Two isozymes were isolated from rat liver by using ion exchange chromatography. These two isozymes were designated as nPTK-I and nPTK-II, and were found to be minor and major components of total nPTK respectively. These proved to be two different enzymes due to their different characteristics, such as molecular weights, electrical charges and kinetics. The specific activity nPTK-I and its percentages in total nPTK significantly increased in preneoplastic stage (week 10) and slightly elevated further in neoplastic stage (week 18). The specific activity of the nPTK-II moderately increased at week 10, but compared to its value at week 10, it decrease at week 18, resulted in gradual decrease of its percentage in total nPTK. These results indicate that rat hepatic nPTK-I and nTPK-II may be related to neoplastic and preneoplastic stages of rat liver respectively.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 26 (1998), S. 627-635 
    ISSN: 0271-2091
    Keywords: arbitrary-order boundary element method ; non-singular formulation ; potential problems ; Engineering ; Numerical Methods and Modeling
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper presents a general direct integral formulation for potential flows. The singularities of Green's functions are desingularized theoretically, using a subtracting and adding back technique, so that Gaussian quadrature or any other numerical integration methods can be applied directly to evaluate all the integrals without any difficulty. When high-order quadrature formulas are applied globally, the number of unknowns can be reduced. Interpolation functions are not necessary for unknown variables in the present paper. Therefore, the present method is much simpler and more efficient than the conventional one. Several numerical examples are calculated and compared satisfactorily with analytical solutions or published results. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 38 (1995), S. 1215-1236 
    ISSN: 0029-5981
    Keywords: hybrid micro-macro analysis ; scale effects ; crack interactions ; boundary element method ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Local analysis schemes capable of detailed representations of the micro-features of a problem are integrated with a macro-scale BEM technique capable of handling complex finite geometries and realistic boundary conditions. The micro-scale effects are introduced into the macro-scale BEM analysis through an augmented fundamental solution obtained from an integral equation representation of the micro-scale features. The proposed hybrid micro-macro BEM formulation allows decomposition of the complete problem into two sub-problems, one residing entirely at the micro-level and the other at the macro-level. This allows for investigations of the effects of the micro-structural attributes while retaining the macro-scale geometric features and actual boundary conditions for the component or structure under consideration. As a first attempt, elastic fracture mechanics problems with interacting cracks at close spacings are considered. The numerical results obtained from the hybrid BEM analysis establish the accuracy and effectiveness of the proposed micro-macro computational scheme for this class of problems. The proposed micro-macro BEM formulation can easily be extended to investigate the effects of other micro-features (e.g. interfaces, short or continuous fibre reinforcements, voids and inclusions, in the context of linear elasticity) on macroscopic failure modes observed in structural components.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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