ISSN:
1432-2307
Keywords:
Lysozyme
;
Enzyme immunohistochemistry
;
Chronic cholecystitis
;
Pseudopyloric glands
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Gallbladders of 12 cases with chronic cholecystitis showing pseudopyloric glands (PPG) and of 18 cases with acute cholecystitis or chronic cholecystitis but without PPG were examined by the peroxidase — antiperoxidase (PAP) method using rabbit antibody against human lysozyme (LM). LM-immunoreactivity was detected in the cytoplasm of PPG and, to a lesser extent, in the pits of epithelial crypts that gave rise to PPG. No LM was found in normal gallbladders; in cases of cholecystitis without PPG, LM-immunoreactivity was restricted to infiltrating inflammatory cells. The presence of LM in PPG suggests that PPG represent functional metaplastic areas, involved in the non-specific defence mechanisms through participation of LM.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00612949
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