ISSN:
1432-0738
Keywords:
Chrysene
;
Metabolism
;
Excretion (urinary and faecal)
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The urinary and faecal excretion of chrysene and its phenolic metabolites after oral, intraperitoneal, intratracheal, and intrapulmonary administration to rats have been studied by means of gas chromatography/mass spectrometry. The metabolite profile was found to depend on the mode of excretion and on the route of administration. In all cases the oxidation of chrysene in the 1,2- or 3,4-position predominates, whereas oxidation in the 5,6-position (K-region) seems be a minor pathway.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00288341
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