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  • 1
    Electronic Resource
    Electronic Resource
    Plasma adrenocorticotrophin and cortisol responses to acute hypoxia at rest and during exercise (1988)
    Springer
    European journal of applied physiology 57 (1988), S. 110-113 
    Details
    ISSN: 1439-6327
    Keywords: Adrenocorticotrophin ; Plasma cortisol ; Exercise ; Acute hypoxia ; Plasma lactate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Plasma adrenocorticotrophin (ACTH) and cortisol (F) concentrations were studied in six male subjects under normoxic (N) and acute hypoxic (H) conditions (altitude 3000 m) in a hypobaric chamber. Comparisons were made at rest, at 15, 30, and 60 min of exercise (65% $$\dot V_{{\text{O}}_{{\text{2max}}} } $$ ), and after a 10 min recovery period. Mean (±SE) resting plasma ACTH levels were significantly higher in H (18.6±5.7 pmol · l−1) than in N (9.6±1.6 pmol · l−1) but no difference in resting plasma cortisol was observed between the two conditions. Both plasma ACTH and F concentrations were significantly increased at 60 min of exercise and during the recovery period under normoxic conditions. Hypoxia did not affect the ACTH response to exercise but reduced cortisol elevation. The changes in plasma cortisol concentration from rest to exercise were significantly correlated to ACTH under normoxic (r=0.89,p〈0.001) but not under hypoxic (r=0.43, NS) conditions. Plasma lactate concentration was higher at the end of exercise in hypoxia (p〈0.01), and no correlation existed between plasma lactate and ACTH levels. These observations provide further evidence that at sea level the increase in plasma cortisol levels during exercise is the result of ACTH-induced steroidogenesis. The responses observed at rest and during exercise in hypoxia suggest that adrenal sensitivity for ACTH may be altered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691248
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Saliva flow and composition in humans exposed to acute altitude hypoxia (1990)
    Springer
    European journal of applied physiology 59 (1990), S. 450-453 
    Details
    ISSN: 1439-6327
    Keywords: Exercise ; Acute hypoxia ; Saliva ; Parasympathetic activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of acute hypoxia (2 days at 4350 m) on whole saliva flow and composition were studied on 12 sea-level natives, at rest and following a maximal exercise. Exercise, performed in normoxia and hypoxia, did not induce variations in saliva flow rate, saliva potassium or α-amylase concentrations. In contrast, acute hypoxia did lead to an increase in mean saliva flow rate both at rest (0.63 ml·min−1 to 0.93 ml·min−1,P〈0.01) and after exercise (0.56 ml·min−1 to 1.06 ml·min−1,P〈0.05) and a decrease in mean saliva potassium concentration at rest (20.8 mmol·1−1 to 14.7 mmol·1−1,P〈0.01) as well as after exercise (21.7 mmol·1−1 to 16.5 mmol·1−1,P〈0.05). This effect might be the consequence of a hypoxia-induced stimulation of the parasympathetic nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02388627
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    Paper (German National Licenses)
    Fulltext
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