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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 267 (1980), S. 47-60 
    ISSN: 1432-069X
    Keywords: Histiocytoma ; Fibroma ; Sclerosing angioma ; Histiocytom ; Fibrom ; Sklerosierendes Angiom
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Überprüft man in Histiocytomen mit Hilfe des Nachweises der alkalischen Phosphatase den Verlauf der Capillaren, so überrascht die große Zahl der Gefäße. Von einem Zentrum erstrecken sich diese durch das ganze Histiocytom, selbst die über dem Histiocytom unter der Epidermis gelegenen Capillaren sind gewuchert. Histochemische und elektronenmikroskopische Untersuchungen zeigen aber, daß die Mehrzahl der Tumorzellen keine Gefäßzellen sind, sondern Fibroblasten, Histiocyten und Mastzellen. Die jüngeren Fibroblasten gleichen Elementen, die man auch bei der Wundheilung findet und die man als C-Fibroblasten bezeichnet hat.
    Notes: Summary In histiocytomas the alkaline phosphatase technique reveals a surprising number of capillaries. The capillaries branch out from the center to the periphery of the histiocytoma and even the capillaries beneath the epidermis proliferate. The cellular elements outside the capillaries, however, are fibroblasts, histiocytes and mast cells, as is revealed by various histochemical and electron microscopical examinations. Histiocytomas of short duration differ from older histiocytomas in that the former contain fibroblasts similar to those found in healing wounds (C-fibroblasts).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 251 (1994), S. 36-40 
    ISSN: 1434-4726
    Keywords: Facial muscle ; Enzyme histochemistry ; Facial palsy ; Experimental denervation ; Reinnervation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The morphological changes in rat facial muscles were evaluated after permanent denervation and were compared with findings after immediate reinnervation. Thirty rats underwent transection of the left and right facial nerves immediately followed by hypoglossal-facial nerve anastomosis on the right side (muscular reinnervation) and removal of 8–10 mm of the facial plexus on the left side (permanent muscular denervation). Levator labii muscle samples of both sides were collected sequentially at 2, 6, 7, 10, 20, and 24 weeks after surgery and submitted to routine histological and enzyme histochemical staining procedures. In normal levator labii muscles a typical “chessboard” pattern was found, with type I fibers being smaller than type II fibers. These latter fibers also were more prevalent than the type I fibers. Among the type II fiber subtypes, the type IIB fibers were larger and more frequent. Two weeks after surgery, there were no differences between denervated facial muscles and those undergoing reinnervation. Both showed atrophic myofibers among normal-sized fibers and slight fibrosis. Those muscles denervated for more than 2 weeks displayed increasing fiber atrophy with frequent loss of typability, as well as proliferation of connective tissue and fat cells in perimysial and endomysial sites. After denervation for 20 weeks only a few atrophic fibers were found in wide areas of fibrosis and fat cells. Following nerve anastomosis the reinnervated levator labii muscle showed much less fiber atrophy. Regrowth to normal fiber diameters was found with only a few atrophic myofibers 10 weeks after anastomosis although a moderate fibrosis predominated at perimysial sites. Reinnervated facial muscle fibers displayed a typical type-grouping pattern and also frequent lack of typability.
    Type of Medium: Electronic Resource
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