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  • 1
    Electronic Resource
    Electronic Resource
    Multiple-population versus hierarchical conifer breeding programs: a comparison of genetic diversity levels (1995)
    Springer
    Theoretical and applied genetics 90 (1995), S. 584-594 
    Details
    ISSN: 1432-2242
    Keywords: Multiple-population breeding (MPBS) Hierarchical open-ended breeding (HOPE) Genetic conservation ; Conifers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Advanced-generation domestication programs for forest-tree species has raised some concerns about the maintenance of genetic diversity in forest-tree breeding programs. Genetic diversity in natural stands was compared with two genetic conservation options for a third-generation elite Pinus taeda breeding population. The breeding population was subdivided either on the basis of geographic origin and selection goals (multiple-population or MPBS option) or stratified according to genetic value (hierarchical or HOPE option). Most allelic diversity in the natural stands of loblolly pine is present in the domesticated breeding populations. This was true at the aggregate level for both multiple-population (MPBS) and the hierarchical (HOPE) populations. Individual subpopulations within each option had less genetic diversity but it did not decline as generations of improvement increased. Genetic differentiation within the subdivided breeding populations ranged from 1 to 5%, genetic variability is within each subpopulation rather than among subpopulations for both MPBS (〉95%) and the HOPE approaches (〉98%). Nei's Gst estimates for amongpopulation differentiation were biased upwards relative to estimates of θ from Weir and Cockerham (1984).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00222007
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Predicting age-age genetic correlations in tree-breeding programs: a case study of Pinus taeda L. (2000)
    Springer
    Theoretical and applied genetics 100 (2000), S. 199-206 
    Details
    ISSN: 1432-2242
    Keywords: Key words Age-age genetic correlations ; Phenotypic correlations ; Conifers ; Tree breeding ; Woody perennials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  A meta-analysis of 520 parents and 51,439 individuals was used to develop two equations for predicting age-age genetic correlations in Pinus taeda L. Genetic and phenotypic family mean correlations and heritabilities were estimated for ages ranging from 2 to 25 years on 31 sites in the southern U.S. and Zimbabwe. Equations for predicting age-age correlations based on P. taeda populations from west and east of the Mississippi River proved statistically different. Both predictive equations proved conservative for validation datasets consisting of younger tests in the U.S. and Zimbabwe. Age-dependent log-linear predictive equations were favored over growth-dependent equations. All P. taeda predictive equations based on genetic correlations favored earlier selection when compared to a generalized conifer predictive equation based on phenotypic correlations. The age-age correlations structure showed stability independent of planting density and across a wide range of family sizes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001220050027
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Sumatriptan decreases food intake and increases plasma growth hormone in healthy women (1997)
    Springer
    Psychopharmacology 129 (1997), S. 179-182 
    Details
    ISSN: 1432-2072
    Keywords: Key words Sumatriptan ; Food intake ; Plasma growth hormone ; Women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied the effect of the 5-HT1B/1D receptor agonist sumatriptan (6 mg SC) on plasma growth hormone and prolactin and food intake in 15 healthy female subjects using a double-blind, placebo-controlled, cross-over design. Sumatriptan significantly elevated plasma growth hormone but did not alter plasma prolactin. Sumatriptan also significantly lowered total food intake in a buffet meal, particularly decreasing the intake of fat. Our results indicate that 5-HT1B/1D receptors may be involved in the regulation of food intake in humans. In addition, while activation of 5-HT1B/1D receptors stimulates growth hormone release in both men and women, sumatriptan lowers plasma prolactin only in men, suggesting sex differences in the 5-HT regulation of prolactin release.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002130050178
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    m-Chlorophenylpiperazine decreases food intake in a test meal (1994)
    Springer
    Psychopharmacology 116 (1994), S. 120-122 
    Details
    ISSN: 1432-2072
    Keywords: Food intake ; 5-HT receptors ; m-Chlorophenylpiperazine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied the effect of the 5-HT receptor agonist,m-chlorophenylpiperazine (mCPP) (0.4 mg/kg), on food intake in 12 healthy female volunteers, in a double-blind placebo controlled design. Compared to placebo, mCPP significantly lowered food intake in a test meal. Treatment with mCPP also caused significant increases in ratings of nausea and light-headedness, though these effects had remitted by the time of the test meal. The results suggest that activation of brain 5-HT2C receptors may lower food intake in humans; it is also possible, however, that the hypophagic effect of mCPP in the present study could be a consequence of its adverse subjective side effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02244883
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    Paper (German National Licenses)
    Fulltext
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