ISSN:
0170-2041
Keywords:
Calcitonin
;
2-Chlorotrityl resin
;
Fragment condensation
;
Resin, 2-chlorotrityl
;
Peptides
;
Amino Acids
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis of Calcitonin Derivatives by Fragment Condensation in Solution and on 2-Chlorotrityl ResinSer2,Val8,Gly33)-human calcitonin (13) was synthesized in 45% yield by sequential assembly of protected fragments on 2-chlorotrityl resin. An analogous synthesis by fragment condensation in solution yielded (Ser2,Val8)-human calcitonin (21) in 10% yield.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199319930139
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