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  • Fraxinus pennsylvanica  (1)
  • Global optimization  (1)
  • Intercellular adhesion molecule-1  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Journal of cancer research and clinical oncology 126 (2000), S. 595-600 
    ISSN: 1432-1335
    Schlagwort(e): Key words Liver cancer ; Tumor metastasis ; Adhesion ; β Peptide ; Intercellular adhesion molecule-1
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Purpose: To study the inhibitory effects of synthetic β peptide on invasion and metastasis of liver cancer. Methods: Membrane-type intercellular adhesion molecule-1 (ICAM-1) expression of SMMC-7721 cultured hepatoma cells (7721 cells) was detected by immunofluorescence cell flowmeter. The adhesion of 7721 cells to fibronectin (FN) was assayed by the MTT method. The adhesion of 7721 cells to 7721 cells, 7721 cells to endothelial cells, and 7721 cells to lymphocyte cells was detected by adhesion assay. LCI-D20 human liver cancer metastasis model in nude mice was used in this experiment. One hundred micrograms of β peptide per mouse were injected subcutaneously after tumor was resected premetastatically or postmetastatically to observe its effect on liver cancer metastasis after hepatectomy. Results: Membrane-type ICAM-1 expression of SMMC-7721 cells treated by β peptide was lower than that of the untreated cells. The adhesion of 7721 cells to FN, 7721 cells to 7721 cells, 7721 cells to endothelial cells, and 7721 cells to lymphocyte cells was also lower in the β peptide group than in the untreated group. Conclusions:β Peptide can block the adhesion of 7721 cells to FN, 7721 cells to some host cells in vitro, and inhibit HCC metastasis of LCI-D20 model posthepatectomy in vivo, so it could potentially act as an anti-metastasis drug.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Plant and soil 77 (1984), S. 183-192 
    ISSN: 1573-5036
    Schlagwort(e): Adaptation ; Adventitious roots ; Ethylene ; Flooding ; Fraxinus pennsylvanica ; Lenticels ; Turgidity ; Water potential ; Water relations
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Summary Fraxinus pennsylvanica Marsh. seedlings that were 150 days old adapted well to flooding of soil with stagnant water for 28 days. Early stomatal closure, followed by reopening as well as hypertrophy of lenticels and formation of adventitious roots on submerged portions of stems appeared to be important adaptations for flood tolerance. Leaf water potential (ψ1) was consistently higher in flooded than in unflooded seedlings, indicating higher leaf turgidity in the former. This was the result of (1) early reduction in transpiration associated with stomatal closure, and (2) subsequently increased absorption of water by the newly-formed adventitious roots as stomata reopened and transpiration increased. Waterlogging of soil was followed by large increases in ethylene content of stems, both below and above the level of submersion. Formation of hypertrophied lenticels and adventitious roots on flooded plants was correlated with increased ethylene production. However, the involvement of various compounds other than ethylene in inducing morphological changes in flooded plants is also emphasized.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Journal of optimization theory and applications 98 (1998), S. 431-448 
    ISSN: 1573-2878
    Schlagwort(e): Global optimization ; partitioned random search ; sequential sampling ; dynamic programming
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Notizen: Abstract The paper studies the optimal sequential sampling policy of the partitioned random search (PRS) and its approximation. The PRS is a recently proposed approach for function optimization. It takes explicitly into consideration computation time or cost, assuming that there exist both a cost for each function evaluation and a finite total computation time constraint. It is also motivated at improving efficiency of the widely used crude random search. In particular, the PRS considers partitioning the search region of an objective function into K subregions and employing an independent and identically distributed random sampling scheme for each of K subregions. A sampling policy decides when to terminate the sampling process or which subregion to be sampled next.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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