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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Pflügers Archiv 351 (1974), S. 133-145 
    ISSN: 1432-2013
    Schlagwort(e): Smooth Muscle ; Pacemaker Activity ; Frog Stomach
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Wick and pressure electrode recording were used to locate the sites where spontaneous activity originates in isolated bundles of the circular smooth muscle layer of frog stomach. In long bundles up to three pacemaker regions were found to be active. Electrical activity of pacemaker regions as recorded with pressure electrodes is characterized by a distinct prepotential which has not been observed to precede action potentials of other regions of the bundle. Pacemaker sites are up to 8 mm away from each other. They appear to be spatially fixed and do not shift with time. When pacemaker regions were excised, we did not observe spontaneous activity in the remaining segments. Stimuli which usually induce activity in latent pacemaker regions are ineffective in such segments. Along the circumference of intact muscle rings of the stomach also three pacemaker regions have been located. Pacamaker frequency increases in aboral direction and is one per minute in the fundus region and 6 per min in the pyloric region.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Pflügers Archiv 351 (1974), S. 147-159 
    ISSN: 1432-2013
    Schlagwort(e): Smooth Muscle ; Frog Stomach ; Excitation Spread ; Spontaneous Activity ; Regional Contraction
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The spread of excitation in isolated bundles of smooth muscle from frog stomach has been measured with movable external electrodes. Amplitudes of the compound action potentials vary along the bundle. They are maximal in pacemaker regions and decrease as a function of distance from the pacemaker. Excitation spread in the bundle is limited and does not exceed 6–7 mm on both sides of a pacemaker region. This distance is independent of the diameter of the bundles. Bathing the bundles in saline with double concentration of potassium (5 mMol/l) does not influence conduction distance. If the bundle is stretched conduction distance increases in proportion to the increase in length. Duration and conduction velocity of the compound action potential remain constant along the region which is activated by one pacemaker. Surface marking with carbon particles revealed that also the degree of shortening varies along the bundle. In the vicinity of a pacemaker region, where compound action potentials have their maximum amplitude, shortening is maximal. Electrical and mechanical activity decay in a similar way along the bundle. A spontaneous isometric contraction was found to consist of a regional shortening while non-active or less active regions were stretched.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Mathematical geology 26 (1994), S. 769-781 
    ISSN: 1573-8868
    Schlagwort(e): cyclic sedimentation ; Fourier stratigraphy ; Milankovitch ; orbital templates ; Quaternary
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie , Mathematik
    Notizen: Abstract A simple template-generating algorithm using summer insolation at 65°N as input provides a timeseries for the last 2 million years that can be compared directly with the oxygen isotope record in deep-sea sediments. Discrepancies between template and record are diminished by representing both series as Fourier expansions, and importing the power spectrum of the record to the template, without changing phase. The remaining differences between the hybrid template and the record contain messages about time spans of unusual behavior of the system. The most striking anomalies in the Quaternary are the unusually cold period following the mid-Pleistocene climate shift at 900 ka (Stage 22) and much of Stage 11 near 400 ka, representing excess warming. The present interglacial also is too warm, compared with expectations. Anomalies are thought to be the result of stabilization of unusually cold periods (by albedo feedback) and unusually warm periods (by carbon dioxide feedback). It is proposed that there is a connection between surplus ice buildup (after the mid-Pleistocene climate shifi at 900 ka) on marine shelves and subsequent extra-large transgressions, which stabilize warm periods by shallow-water carbonate production (coral reef hypothesis).
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    International journal of earth sciences 88 (1999), S. 305-316 
    ISSN: 1437-3262
    Schlagwort(e): Key words Quaternary ; Milankovitch ; 100-kyr cycles ; Eccentricity ; Inclination ; Ice age cycles
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie
    Notizen: Abstract The ice-age hypothesis of Muller and MacDonald (1995, 1997a, 1997b) has two parts: (a) The 100-kyr cycle does not owe its existence to Milankovitch forcing; and (b) variations in inclination of Earth's orbit (i.e., the orbit's angle with the solar system invariable plane) provide the mechanism sought. In support of the first proposition, Muller and MacDonald point to the paradox that the spectrum of oxygen isotope series from deep-sea sediments contains no power for two prominent eccentricity cycles, 125 and 400 kyr. In support of the second proposition, they offer a match between the SPECMAP record (Imbrie et al. 1984) and a plot of the amplitude of orbital inclination, shifted by 33 kyr. The hypothesis of Muller and MacDonald is rejected in both parts, although an influence of inclination forcing is not precluded entirely. The paradox of the missing eccentricity cycles (125 and 400 kyr) is explained by suppression of the two longer cycles, and enhancement of the one near 96 kyr, as a result of internal oscillation. A Muller–MacDonald machine for making the 100-kyr ice-age cycles, however conceived, would have to have a memory near 30 kyr to provide for phase shift between input and output. Precisely this amount of memory is sufficient to produce the needed oscillation in Milankovitch machine here applied; thus, there is no advantage, from the point of view of either necessity or simplicity, in replacing Milankovitch forcing, with its precise phasing (despite the fuzzy physics), with inclination forcing, and with its severe problems in phasing (and, thus far, no physics at all).
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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