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Digitale Medien

The sequence-specific nuclear matrix binding factor F6 is a chicken GATA-like protein (1993)

Vassetzky, Y. S. ; Moura Gallo, C. V. ; Bogdanova, A. N. ; [weitere]

Springer

Molecular genetics and genomics 238 (1993), S. 309-314

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Details

ISSN: 1617-4623

Schlagwort(e): Nuclear matrix attachment ; GATA ; Chicken globin genes ; DNA-binding protein

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Abstract The sequence-specific DNA-binding protein factor F6, which binds upstream of the cluster of the chicken α-globin genes, has previously been found to interact with a DNA fragment containing a replication origin and a nuclear matrix binding site. This protein has been partially characterized. Based on its molecular weight and binding affinity, F6 belongs to a family of GATA proteins, the chicken equivalent of transcription factor NFE-1. An oligonucleotide including the binding site for F6 competes for binding of the above-mentioned DNA fragment to the nuclear matrix. This indicates an involvement of this protein in the interaction between DNA and the nuclear matrix.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00291988

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