Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Immunohistochemical studies on cellular character of microtumors induced by ethylnitrosourea in the rat brain utilizing anti-leu 7 and anti-glial fibrillary acidic protein antibodies (1985)
    Springer
    Acta neuropathologica 66 (1985), S. 167-169 
    Details
    ISSN: 1432-0533
    Keywords: Rat ; ENU ; Brain tumor ; Anti-Leu 7 ; GFAP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To clarify the chronologic changes in the cellular morphology of ENU-induced rat brain tumors, microtumors in the early stage were examined ummunohistochemically in comparison with macrotumors in the advanced stage. The tumor cells composing microtumors were negative for glial fibrillary acidic protein (GFAP), a specific marker of astrocylic cells, and Leu 7, a marker of oligodendrocytes, while cells of macrotumors were positive for either GFAP or Leu 7, showing characteristics of mature glial cells. The results suggested that the small round cells in the early devolopmental stage, generally thought to resemble mature oligodendrocytes, are not differentiated oligodendrocytes or astrocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688694
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Choroid plexus papilloma and giant cell glioblastoma induced in hamsters with bovine adenovirus type 3 (1985)
    Springer
    Acta neuropathologica 66 (1985), S. 218-222 
    Details
    ISSN: 1432-0533
    Keywords: Choroid plexus papilloma ; Giant cell glioblastoma ; Bovine adenovirus type 3 ; Hamster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Newborn hamsters were inoculated with 0.02 ml of bovine adenovirus type 3 (BAV 3) having a titer of 104.5TCID50/0.1 ml. Of 82 hamsters observed over 40 days after viral inoculation, 15 developed choroid plexus papilloma after a latency period of 41–228 days and six developed giant cell glioblastoma after a latency period of 66–214 days. Multiple foci of abnormal cell grwoth were also observed in the meninges and choroid plexus. Choroid plexus papilloma developed in the ventricles occupying the ventricular cavity and histologically showed a radiating arrangement of spindle-shaped cells forming perivascular pseudorosettes. Giant cell glioblastoma developed in the cerebral cortex including the meninges. The tumors were reddish in color and soft in consistency. Histologically, the tumor cells were short-spindle, ovar or, pleomorphic cells with a large vesicular nucleus, and were characterized by the appearance of monster cells and hypervascularity. The short spindle-shaped cells were positive for glial fibrillary acid protein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688586
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...