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  • 1
    Electronic Resource
    Electronic Resource
    The TRAIL of Death (1998)
    Springer
    Apoptosis 3 (1998), S. 83-88 
    Details
    ISSN: 1573-675X
    Keywords: Apoptosis ; TNF ; TRAIL
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The TNF ligand family member termed TRAIL has been shown to induce apoptosis in a wide variety of transformed cell lines. The normal functions of this cytokine in vivo remain, however, relatively unknown. The complexity of this biological system has now increased unexpectedly with the identification of four distinct receptors for TRAIL, two of which have cytoplasmic death domains. This review will describe the known biological effects of TRAIL, as well as the structure and possible functions of its recently identified receptors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009640823621
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Intracellular levels of polyadenylated RNA and loss of vigour in germinating wheat embryos (1982)
    Springer
    Planta 156 (1982), S. 413-420 
    Details
    ISSN: 1432-2048
    Keywords: Embryo vigour ; Germination (embryo) ; Poly(A) RNA ; Vigour (seed) ; Triticum (seed vigour)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Polyadenylated-RNA (Poly(A)+RNA) levels have been studied during the germination of wheat embryos of high viability but differing vigour. In high-vigour embryos imbibed at 20°C the level of poly(A)+RNA falls dramatically over the first hour of imbibition, then remains constant up to 3 h of imbibition before increasing rapidly to a level similar to that found in the quiescent state by 7 h of imbibition. Median-vigour embryos imbibed at 20°C show similar changes in poly(A)+RNA content but the initial decrease and subsequent increase in poly(A)+RNA levels are less marked. On imbibition at 10°C, the poly(A)+RNA content in high-vigour embryos decreases to a lesser extent during the first hour than at 20°C and the level increases more slowly over the next 6 h than during the same time period at 20°C. The level of poly(A)+RNA in medianvigour embryos remains constant over the first 4 h of germination and then falls to a level of about half that found in quiescent high-vigour embryos. Polyacrylamide gel electrophoresis of total-RNA samples shows that the polyadenylic acid (poly(A)) sequences occur in RNA species ranging in size from 35-7S. Polyacrylamide gel electrophoresis of isolated poly(A) sequences demonstrates the presence of two size classes of poly(A) in quiescent embryos, but at 20°C a more heterodisperse pattern appears by 2 h of imbibition. At 10°C, two size classes of poly(A) persist throughout the period studied in both high- and median-vigour embryos, although in median-vigour embryos the ratio of larger: smaller poly(A)-tail sizes decreases more rapidly than in high-vigour embryos.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00393312
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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