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  • HLA-DR antigens  (2)
  • Blutspuren, HLA-System  (1)
  • 1
    Digitale Medien
    Digitale Medien
    HLA-DR antigens and disease patterns of rheumatoid arthritis (1983)
    Springer
    Rheumatology international 3 (1983), S. 113-116 
    Details
    ISSN: 1437-160X
    Schlagwort(e): HLA-DR antigens ; Rheumatoid arthritis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary HLA-DR antigens were determined in 111 patients with classic or definite rheumatoid arthritis. HLA-DR4 was significantly (P corr. 〈10−6) increased in patients with rheumatoid arthritis (54%) compared with controls (23.2%). HLA-DR 5 was decreased in rheumatoid arthritis (12.6% vs 26.4% of controls); however, the corrected P value was not significant. There were no significant differences with regard to various clinical, radiological and serological parameters between HLA-DR 4 positive and negative patients. However, a milder course of rheumatoid arthritis was observed in DR 7 positive patients: Patients with this antigen were associated significantly with seronegativity and low titers of IgM-rheumatoid factor. Despite a similar disease duration patients with DR 7 had a significantly lower number of joints with inflammatory arthritis (synovitic swelling with limitation of movement) and developed less frequently severe radiological changes as joint ankylosis than DR 7 negative patients. In addition to the well known association between rheumatoid arthritis and HLA-DR 4, our data indicate that HLA-DR 7 may have a protective effect on the course of rheumatoid arthritis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00541190
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    The detection of HLA antigens in bloodstains (1988)
    Springer
    International journal of legal medicine 101 (1988), S. 209-217 
    Details
    ISSN: 1437-1596
    Schlagwort(e): HLA system, detection in bloodstains ; Bloodstains, HLA system ; HLA System, Nachweis in Blutspuren ; Blutspuren, HLA-System
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Rechtswissenschaft
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Nach einer Beschreibung der Genetik des HLA Systems wird die Möglichkeit der HLA-Typisierung von Blutspuren diskutiert.
    Notizen: Summary After a survey of the genetics of the HLA system, the possibility to type bloodstains for HLA gene products is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00200226
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  • 3
    Digitale Medien
    Digitale Medien
    HLA-DR in meningopolyneuritis of garin-bujadoux-bannwarth: contrast to lyme disease? (1984)
    Springer
    Journal of neurology 231 (1984), S. 271-272 
    Details
    ISSN: 1432-1459
    Schlagwort(e): Meningopolyneuritis of Garin-Bujadoux-Bannwarth ; Bannwarth's syndrome ; Lyme disease ; Histocompatibility antigens ; HLA-DR antigens
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Sixteen patients with meningopolyneuritis of Garin-Bujadoux-Bannwarth (MPN-GBB) were examined for HLA-DR antigens. In contrast to data in Lyme disease (LD), which is caused by an identical or closely related spirochete, no significant association was found between the neurological disease and HLA-DR. The reported association between neurological disease and HLA-DR2 in LD may be due to the inclusion of cases with neurological disease and arthritis, since chronic arthritis in LD seems to be well correlated with HLA-DR2.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00313666
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