ISSN:
1432-1246
Schlagwort(e):
Epoxy resin
;
Hexahydrophthalic anhydride
;
Hexahydrophthalic acid
;
Urinary excretion
;
Biological monitoring
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Summary Post-shift and next-morning urine was sampled from workers exposed to hexahydrophtalic anhydride (HHPA), an epoxy hardener, sensitising at low exposure levels. Exposure levels of HHPA in air gas chromatography, GC) in the range of 30–270 μg/m3 corresponded to urinary concentrations of 0.9–2.8 μmol hexahydrophthalic acid (HHP acid; GC-mass spectrometry)/mmol creatinine. In the morning samples the concentrations were 〈0.04-0.3 μmol HHP acid/mmol creatinine. In unexposed controls, the level was 〈0.1 μmol/mmol creatinine. A correlation was found between the time-weighted levels of HHPA in air and HHP acid in the post-shift urine (r s = 0.93; P 〈 0.023), indicating that the determination of HHP acid in urine is suitable for biologic monitoring of HHPA exposure.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00406202
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