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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 12 (1969), S. 33-41 
    ISSN: 1432-0533
    Keywords: Swayback ; Spinal Cord White Matter ; Myelin Breakdown ; Histochemistry ; Biochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Elf Schafe mit Swayback im Alter von 2, 3 1/2, 6 1/2 und 8 Monaten sowie 10 Normaltiere gleichen Alters wurden untersucht. Die Histopathologie und Biochemie der weißen Substanz des Rückenmarks wurde ausführlich studiert. Im Rückenmark der kranken Tiere lag weniger Myelin und ein geringerer Gehalt an Cerebrosiden und Ethanolamin-Phospholipid als in den Kontrollen vor. Markscheidenzerfallsprodukte wurden nur bei älteren Tieren gefunden, wobei gute Übereinstimmung der Ergebnisse der OTAN-, Sudan II- und Marchi-Methoden bestand. Die Befunde werden hinsichtlich ihrer Beziehung zur Pathogenese der Läsion diskutiert.
    Notes: Summary Eleven sheep with swayback aged 2, 3 1/2, 6 1/2 and 8 months, and 10 normal sheep of similar age were examined. The histopathology and biochemistry of the spinal cord white matter was studied in detail. There was less myelin in the spinal cord white matter of the swayback animals and it had a lower content of cerebroside and ethanolamine phospholipid than that of the controls. Myelin breakdown products were only found in the older animals and there was a close correlation between the results obtained by the OTAN, Sudan II and Marchi techniques. These results are discussed in relation to the pathogenesis of the lesion.
    Type of Medium: Electronic Resource
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