ISSN:
1432-0878
Schlagwort(e):
Circumventricular organs
;
Reticuloendothelial system
;
Phagocytic cells
;
Horseradish peroxidase
;
Cat
;
Rat
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary The structure of mesenchymal cells distributed in some of the “hypendymal organs” of the circumventricular system in the cat and rat was demonstrated after intravenous injection of high doses of horseradish peroxidase. These cellular elements were observed in the vicinity of blood vessels of the organon vasculosum laminae terminalis, subfornical organ and area postrema. Electron-microscopically, these cells located between the basal laminae of the brain parenchyma and the blood capillaries show long cellular processes encircling fenestrated capillaries. Light and electron-microscopic examination revealed that this cell type is identical with the “horseradish peroxidase-uptake cells”, previously reported in the vicinity of the hypophysial portal system. Such phagocytic cells may be considered as a cellular component intervening between the brain parenchyma and the blood stream, playing a role in selective barrier functions in the above-mentioned circumventricular organs where a blood-brain barrier in the classical sense of the definition is lacking.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00210020
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