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Digitale Medien

Human papillomavirus type 16 DNA detected by the polymerase chain reaction in non-cancer tissues of the head and neck (1994)

Fukushima, K. ; Ogura, H. ; Watanabe, S. ; [weitere]

Springer

European archives of oto-rhino-laryngology and head & neck 251 (1994), S. 109-112

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Details

ISSN: 1434-4726

Schlagwort(e): Human papillomavirus ; Head and neck cancer ; Polymerase chain reaction ; Southern blot hybridization

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Cancer-free tissues from various anatomical subsites in the head and neck were examined by the polymerase chain reaction (PCR) for the incidence of human papillomavirus (HPV) types 16 and 18. We detected HPV 16 DNA in 9 of 103 samples (8.7%), including specimens from the paranasal sinuses, tonsil, hypopharynx and larynx. However, no HPV-16/18 DNA was detected by Southern hybridization in these 9 samples. The significance of the presence of HPV 16 DNA in non-cancer tissues is still unknown, but PCR detection only of high-risk HPV DNA in head and neck cancer should be evaluated cautiously because of its ubiquity in this region.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00179903

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