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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 244 (1989), S. 169-173 
    ISSN: 1432-0711
    Keywords: Hysterectomy ; Hypergonadotropism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The serum levels of FSH, LH and estradiol-17β (E2) were determined in 110 women aged between 38–48 years who had been hysterectomized 2–10 years previously and were compared with a control group (n=112). In hysterectomized women both FSH and LH levels were higher than in controls during the whole 12 year period. These differences were significant up to 43 years of age. The hypergonadotropism in hysterectomized women correlates with the higher incidence of climacteric symptoms reported in the literature.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 226 (1978), S. 363-368 
    ISSN: 1432-0711
    Keywords: Hysterectomy ; Ovarian function ; Premenopause ; Hormonal cycle ; Hysterektomie ; Ovarialfunktion ; Pramenopause ; Zyklus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 48 Frauen nach Hysterektomie im Alter von 28–43 Jahren wurden 5–10 Jahre später Plasmabestimmungen von FSH, LH, Östradiol-17β und Progesteron durchgeführt. Zum Vergleich diente eine Gruppe prämenopausaler Frauen mit fluktuierender FSH-Erhöhung und eine weitere mit stabilem Hypergonadotropismus. Es wurde festgestellt, daß nach Hysterektomie bei den Frauen unter 40 Jahren stets, zwischen 41 und 45 Jahren in drei Viertel und mit mehr als 46 Jahren in der Hälfte eine normogonadotrope und normosteroidale Ovarialfunktion vorlag. Die Frauen mit fluktuierendem oder stabilem Hypergonadotropismus waren jedoch nach Hysterektomie durchschnittlich um 2 Jahre jünger als die prämenopausalen Frauen mit entsprechender Ovarialfunktion. Eine gewisse zeitliche Vorverlegung von nachweisbaren Kriterien einer definitiven Ovarialinsuffizienz war bei einem Teil der Frauen damit nicht auszuschließen.
    Notes: Summary Plasma-FSH, -LH, -Estradiol-17β, and -Progesterone were determined weekly in women aged between 28 and 43 years who had been hysterectomized 5–10 years before. The endocrine parameters were compared with those of women with a normal cycle and two groups of premenopausal women, the one showing a fixed hypergonadotropic state, the other slightly elevated but still cyclic fluctuations of FSH and normal LH values. After hysterectomy, normal ovulatory cycles were found in all women of up to 40 years, in 75% of those between 41 and 45 years and in 50% of those beyond 46 years. The average age of women with fluctuating or fixed hypergonadotropism was 2 years less in the hysterectomiced group. Thus, a certain acceleration of ovarian insufficiency caused by hysterectomy cannot be denied.
    Type of Medium: Electronic Resource
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