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  • 1
    Electronic Resource
    Electronic Resource
    Treatment of idiopathic thrombocytic purpura in pregnancy by high-dose intravenous immunoglobulin (1983)
    Springer
    Annals of hematology 46 (1983), S. 347-353 
    Details
    ISSN: 1432-0584
    Keywords: ITP ; ITP in pregnancy ; High-dose immunoglobulin therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary ITP in pregnancy may lead to fetal thrombocytopenia caused by the transplacental passage of maternal antiplatelet antibody. The most hazardous complication in the infant is intracranial hemorrhage. In addition ITP in pregnancy is reported to be associated with an increased abortion rate and an elevated fetal morbidity and mortality. Therefore obstetric management must aim at increasing maternal and fetal platelets. Severel therapeutic approaches to the treatment of ITP in pregnancy are evaluated. Two cases of ITP in pregnancy are reported. Administration of high-dose intravenous immunoglobulin is introduced as a new therapy for ITP in pregnancy. The rapid reversal of thrombocytopenia following immunoglobulin G administration suggests that it is useful especially as emergency treatment for ITP in pregnancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00320695
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The place of intravenous immunoglobulin (IgG i.v.) therapy in thrombocytopenia (1984)
    Springer
    Annals of hematology 48 (1984), S. 409-413 
    Details
    ISSN: 1432-0584
    Keywords: Acute postinfectious ITP ; Chronic idiopathic thrombocytopenic purpura ; Immunoglobulin therapy ; Steroid therapy ; ITP in pregnancy ; Neonatal thrombocytopenia ; Neonatal isoimmune thrombocytopenia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Acute ITP following infection in children has a high rate of spontaneous remission. Since the platelet count is not uncommonly profoundly depressed, ITP is associated with a mortality of around 1%. The aim of treatment in ITP is to prevent bleeding. As a rule, this can only be achieved by normalizing the platelet count. Intravenous immunoglobulin offers certain advantages over conventional steroid therapy. Moreover, two out of three patients with chronic ITP respond to IgG i.v. The characteristic features of ITP in pregnancy, thrombocytopenia in babies born to mothers with ITP and neonatal isoimmune thrombocytopenia are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319973
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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