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  • 1
    ISSN: 1432-2307
    Keywords: Malignant and benign lymphoma ; Immunocytoma ; Centroblastic malignant lymphoma ; Castleman Tumor ; Eye, lid and orbit ; Histologic features
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In der vorliegenden Studie wurden 23 Lymphome der Augen-, Lid- und Orbitalregion ausgewertet. Sie stammten aus einem nicht ausgewählten bioptischen Untersuchungsgut des Pathologischen Instituts der Universität Kiel und des Lymphknotenregisters bei der Deutschen Gesellschaft für Pathologie. Es handelte sich dabei um 12 maligne und 11 benigne Lymphome. Die malignen Lymphome stellten jeweils Non-Hodgkin-Lymphome dar. Unter den letzteren fanden wir elfmal ein Immunocytom, ein malignes Lymphom mit niedrigem Malignitätsgrad — dagegen nur einen Fall eines malignen Lymphoms mit hohem Malignitätsgrad, ein centroblastisches Lymphom. Die Diagnose eines benignen Lymphoms wurde jeweils durch die von uns erhobenen katamnestischen Angaben bestätigt. Während sich das benigne Lymphom in 7 von 11 Fällen in der Conjunctiva entwickelt hatte, war dies bei nur 2 von 11 Fällen mit Immunocytom zu beobachten. Das Immunocytom stellt einen Tumor dar, der aus Lymphocyten und Plasmazellen oder plasmocytoiden Zellen besteht und meist PAS-positive globuläre Einschlüsse in Kern und/oder Cytoplasma der Plasma- oder plasmocytoiden Zellen aufweist.
    Notes: Summary Twenty-three lymphomas of the eye, eyelid, and orbit were chosen for study from biopsy material of the Department of Pathology, University of Kiel, and the Lymph Node Registry in Kiel. There were 12 malignant non-Hodgkin's lymphomas and 11 benign lymphomas. Catamnestic examination confirmed the histologic diagnosis in all 11 cases of benign lymphoma. Eleven of the malignant lymphomas represented immunocytomas and were therefore of low-grade malignancy. In contrast, there was only one case of malignant lymphoma of high-grade malignancy, which was diagnosed as centroblastic lymphoma. The immunocytoma was retrobulbar in one third of our cases and conjunctival in only 2 cases, whereas benign lymphoma had developed in the conjunctiva in 7 of 11 cases. Immunocytoma represents a tumor composed of lymphocytes and plasma cells or plasmacytoid cells. PAS-positive globular inclusions are usually found in the nucleus and/or cytoplasm of the plasma cells or plasmacytoid cells.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 373 (1977), S. 303-309 
    ISSN: 1432-2307
    Keywords: Immunocytoma ; Malignant lymphoma, lymphoplasmacytoid ; Chronic lymphocytic leukemia ; Tissue mast cell count and distribution ; Differential diagnostic parameters in lymph node biopsies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The amount and distribution of tissue mast cells in the three subtypes of immunocytoma (IC) were studied in lymph nodes of 58 cases and compared with the findings on 34 cases of chronic lymphocytic leukemia (CLL). There were significantly more mast cells in the lymphoplasmacytic and lymphoplasmacytoid subtypes of IC than in CLL. The median mast cell count for the polymorphic subtype of IC was also greater than that for CLL; however, this difference was not statistically significant. Tissue mast cells were diffusely distributed in the lymph nodes in IC, whereas they were chiefly located in the sinus in CLL. Moreover, the cells themselves and their granules were generally larger in IC. Increase in the number and altered distribution of the tissue mast cells in histological sections are therefore diagnostic aids for distinguishing IC from CLL.
    Type of Medium: Electronic Resource
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