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  • 1
    ISSN: 1434-0879
    Keywords: Prostatic acid phosphatase ; Lysosomes ; Prostatic antigen ; Immunoelectron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ultrastructural localization of secretory prostatic acid phosphatase (PAP) in human benign prostate tissue was accomplished using the immunogold technique on ultrathin Lowicryl sections. Polyclonal antibodies directed against secretory PAP (MW 50 kD) and the lysosomal enzymes α-glucosidase and β-galactosidase as well as an antiserum dircted against prostatic antigen (PA) were used. PAP was found in secretory vacuoles of columnar secretory epithelial cells. In addition, double labeling experiments revealed that secretory PAP was also localized in electrondense organelles of columnar epithelial cells containing α-glucosidase and β-galactosidase. PA was exclusively found in secretory vacuoles of columnar secretory epithelial cells. The results demonstrate the presence of secretory PAP within functional lysosomes and secretory vacuoles of the prostatic columnar epithelial cells and the absence of such PAP-containing lysosomes in the basal cells of the prostatic acini.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: Key words: Esophagus ; Esophageal tumor ; Giant esophageal polyp ; Fibrovascular polyp ; Liposarcoma ; Lipoma ; Hamartoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Giant pedunculated esophageal polyps are very rare. They may stay asymptomatic for a long time, and first come to the attention of the patient and the clinician after regurgitation into the mouth. Regurgitation, however, can be dangerous and has been known to lead to asphyxia and death due to closure of the larynx by the polyp mass. For this reason resection of the giant polyp is essential when it is discovered. We have seen four cases of giant esophageal polyps (GEP) at our institution. All four patients have undergone removal of the giant polyps. The histological diagnoses were fibrovascular polyp, liposarcoma, hamartoma and multiple lipomas. The mode of clinical presentation, radiological appearances, variable histological diagnoses, and therapy options in these four patients are presented along with a review of the literature.
    Type of Medium: Electronic Resource
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