ISSN:
1432-1440
Keywords:
T-cell subsets
;
Helper/suppressor ratio
;
Immunotherapy
;
Immunomodulation
;
Heterologous antigen, PIND-AVI
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The immunomodulating effect of a new heterologous antigen (PIND-AVI) on helper (inducer) and suppressor T cells was investigated. Primarily decreased T4 values $$\left( { \leqslant \overline X _{T4} - 2S.D.} \right)$$ increased after treatment with PIND (P〈0.005, using Student'st-test;n=15). Primarily increased T8 values ( $$ \geqslant \overline X _{T8} + 2S.D.$$ ; obtained for normal persons) decreased after therapy (P〈0.001;n=10). An increase of T4/T8 ratio (P〈0.005 and 〈0.001) to normal values was observed in both cases. T4 and T8 values within the mean ±2 S.D. were not influenced significantly (n=13). In spite of different primary values, the amount of lymphocytes/mm3 was not significantly influenced. It appears advisable to check the results of treatment continuously every few weeks.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01728460
Permalink
