ISSN:
1432-2307
Keywords:
Large cell anaplastic lymphoma
;
Electron microscopy
;
Immunophenotyping
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Eleven cases of large cell anaplastic lymphoma (T typen=5, B typen=4, 0 typen=2) were investigated using electron microscopy and immunophenotyping on formalin-fixed paraffin sections and frozen sections of fresh tissue, to determine whether morphological criteria exist for the discrimination of T, B, and 0 phenotypes. Tumour cell lineage could not be established from ultrastructural features. On paraffin material monoclonal B-cell markers Ki-B5 and L-26 served as reliable tools for recognizing the B phenotype of large cell anaplastic lymphomas (previously determined on fresh material), whereas monoclonal antibodies MT1 (CD43) and UCHL1 (CD45RO) were of limited value in lineage determination.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01605929
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