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  • 1990-1994  (4)
  • Infancy  (2)
  • Lycopersicon esculentum  (2)
  • 1
    Digitale Medien
    Digitale Medien
    Has modern management improved the outcome of infants with intracranial tumours? (1990)
    Springer
    Child's nervous system 6 (1990), S. 327-330 
    Details
    ISSN: 1433-0350
    Schlagwort(e): Infancy ; Intracranial tumour ; CT scan ; Radiotherapy ; Chemotherapy ; Long-term outcome
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Records of 92 children were reviewed who, in the first 18 months of life had an intracranial tumour, and who were registered with the Manchester Children's Tumour Registry during the 34-year period from 1953 to 1987. The incidence of intracranial tumour was 1 in 25000 live births, and 85% of the tumours were malignant. The introduction of computed tomography (CT) in the region in 1976 improved the diagnostic accuracy and led to early diagnosis. This also coincided with refined radiotherapy and improved chemotherapy. The surgical attitude became more aggressive, and with early treatment, mortality was reduced, though the 1-month operative mortality still remains high at 15%. All survivors were available for follow-up. All children with axial tumours died within 9 years. Long-term follow-up did not suggest significant improvement in the overall survival or in the quality of life, though there was a significant improvement in the 5-year survival rate with modern management.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00298278
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  • 2
    Digitale Medien
    Digitale Medien
    Intracranial tumours in the first 18 months of life (1990)
    Springer
    Child's nervous system 6 (1990), S. 371-374 
    Details
    ISSN: 1433-0350
    Schlagwort(e): Infancy ; Intracranial tumour ; Hereditary factors
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract There are few population-based studies of intracranial tumours in children. This study examines 93 brain tumours in children up to 18 months of age from over 800 childhood central nervous system tumours reported to the Manchester Children's Tumour Registry during the period 1953–1987. The incidence was 1 per 25 000 live births. Of these tumours, 85% were malignant. The three most common tumours were medulloblastoma, ependymoma and juvenile astrocytoma. Eighteen percent of the tumours were in the axial region. Twenty-five percent were connected to the ventricles. The tumour was supratentorial in two-thirds of the children under 6 months of age. A high incidence of tumours in the families of these children was found; tumours were noted in two sets of siblings.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00302220
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Genetic analysis of salt tolerance during germination in Lycopersicon (1991)
    Springer
    Theoretical and applied genetics 81 (1991), S. 321-326 
    Details
    ISSN: 1432-2242
    Schlagwort(e): Lycopersicon esculentum ; Salt tolerance ; Seed germination ; Maternal effects ; Tomato improvement ; Gene action
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary The salt-tolerant cultivated tomato (Lycopersicon esculentum) accession, ‘PI174263’, and a sensitive cv, ‘UCT5’, were crossed to develop reciprocal F1, F2 and BC1 populations for genetic analysis of salt tolerance in tomatoes during seed germination. Variation was partitioned into embryo, endosperm and maternal (testa and cytoplasmic) components. Generation means analysis indicated that there were no significant embryo (additive, dominance or epistatic) effects on germination performance under salt stress. Highly significant endosperm additive and testa dominance effects were detected. The proportion of the total variance explained by the model containing these two components was R2=98.2%. Variance component analysis indicated a large genetic variance with additive gene action as the predominant component. Furhter inspection indicated that this variance was attributable to endosperm additive effects on germinability under salt stress. Narrow-sense heritability was estimated as moderately high. Implications for breeding procedures are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00228671
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  • 4
    Digitale Medien
    Digitale Medien
    Generation means analysis of right-censored response-time traits: Low temperature seed germination in tomato (1990)
    Springer
    Euphytica 48 (1990), S. 239-244 
    Details
    ISSN: 1573-5060
    Schlagwort(e): Lycopersicon esculentum ; tomato ; cold tolerance ; seed germination ; genetic analysis ; missing data ; response-time data
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Summary In studies to determine the inheritance of response-time traits, such as time to seed germination, some viable individuals may fail to respond during an experiment. If these right-censored observations are ignored, sample means and variances will be underestimated. This is illustrated using data from time to seed germination at 9°C for Lycopersicon esculentum (Mill.) fast germinating PI 120256, slow-germinating T3 and their reciprocal F1, F2 and backcross progeny. This paper presents methods to detect and to accommodate right-censored data in generation means analysis. Genetic interpretations derived from corrected and uncorrected estimates of generation means and variances are compared. Correction for right-censoring increased estimates of environmental and phenotypic variances, and decreased heritability estimates.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00023656
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