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  • 1
    Electronic Resource
    Electronic Resource
    Effect of insulin and prednisolone on transport of organic substances in the dog kidney (1978)
    Springer
    Bulletin of experimental biology and medicine 86 (1978), S. 1621-1624 
    Details
    ISSN: 1573-8221
    Keywords: Insulin ; prednisolone ; glucose reabsorption ; tubular secretion ; excretion of sodium by the kidney
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract In experiments on dogs a single injection of insulin in a dose of 1 unit/kg body weight caused an increase in the maximal reabsorption of glucose and secretion of diodone and reduced the excretion of sodium without any change in glomerular filtration. These effects depend on the direct action of insulin, for when it was injected directly into one of the renal arteries its action was manifested only in the kidney on the side of infusion. Prednisolone had no significant effect on glucose and diodone transport when given as a single injection (3–4 mg/kg) or over a period of 10 days (1.5–2 mg/kg daily).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00801820
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    State of the pancreatic islets, fetal weight, and glucose tolerance test in offspring of male rats with alloxan diabetes (1974)
    Springer
    Bulletin of experimental biology and medicine 78 (1974), S. 999-1001 
    Details
    ISSN: 1573-8221
    Keywords: alloxan diabetes ; heredity ; pancreas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The body weight and morphometric parameters of the state of the pancreatic insular apparatus (the relative percentage of islet tissue, of A- and B- cells, the number of islets) in fetuses and the adult offspring of healthy female rats and male rats with alloxan diabetes were studied. No change in these parameters was found, indicating that under these conditions the genetic systems of the males are undamaged and that these lesions are not transmitted to the progeny. On the basis of these findings and of the importance of diabetes in the female in the development of insular deficiency in the progeny demonstrated previously, the role of the environment in which the fetus develops in the formation of the diabetes is emphasized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00796647
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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