ISSN:
1432-0533
Keywords:
Meningioma
;
Brain neoplasms
;
Tissue culture
;
Cells, cultured
;
Intercellular junctions
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Cultured cells derived from a psammomatous meningioma were induced to from whorls in vitro by deprivation of nutrients. The ultrastructural features of desmosomes and junctional complexes were similar to sections from the surgical specimen; also prominent were 9–10 nm cytoplasmic filaments. Microelectrode recording of whorled cells showed a larger resting membrane potential than that of similar isolated meningioma cells in culture. Whorl formation seen in this tumor may be a result of relative nutritional deprivation and the need for metabolic cooperation among tumor cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00684801
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