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Intraneural injection of lymphocytes in experimental allergic neuritis (1983)

Gilbert, J. J. ; Feasby, T. E. ; Hahn, A. F. G.

Springer

Acta neuropathologica 61 (1983), S. 61-64

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ISSN: 1432-0533

Keywords: Experimental allergic neuritis ; Lymphocytes ; Passive transfer ; Intraneural injection

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Passive transfer of experimental allergic neuritis (EAN) lymph node cells (LNC) by intraneural injection did not produce significant demyelination. EAN-LNC stimulated with myelin in vitro produced mild demyelination while those incubated with Concanavalin A had no effect. The lack of demyelination by unstimulated EAN-LNC is in contrast to the marked demyelination produced by intraneural injection of EAN serum. The mononuclear cell infiltration and demyelination of classical EAN seem to require both cellular and humoral immune responses.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00688387

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