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  • 1990-1994  (2)
  • Keratinocytes  (1)
  • nickel  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Growth advantage by overexpression of normal Harvey ras proto-oncogene in cultured rat epidermal keratinocytes (1990)
    Springer
    Archives of dermatological research 282 (1990), S. 330-334 
    Details
    ISSN: 1432-069X
    Schlagwort(e): Harvey ras proto-oncogene ; Gene expression ; Keratinocytes ; Cell growth control
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The ras proto-oncogene is frequently amplified and overexpressed in the hyperproliferative conditions of epidermal keratinocytes. To investigate the effects of its overexpression on the growth of keratinocytes in a model system, we constructed expression vectors for normal human Ha-ras and introduced them into FRSK cells, a fetal rat epidermal keratinocyte cell line. Several clones containing the transfected Ha-ras were isolated, and two of them overexpressed this gene. In these clones DNA synthesis and cell growth were greater than in other clones expressing this gene at low levels. Thus we suggest that overexpression of normal ras gene may provide growth advantage to epidermal keratinocytes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00375728
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Effect of hydrogen on carbon deposition from carbon monoxide on nickel catalyst (1994)
    Springer
    Catalysis letters 23 (1994), S. 237-243 
    Details
    ISSN: 1572-879X
    Schlagwort(e): Carbon deposition ; hydrogen effect ; nickel
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Abstract The role of hydrogen in carbon deposition on Ni has been studied at H2/CO 〈 1 and 698 K by determining the respective rates of the carbon-forming reactions: (1) CO + H2 →-C + H2O and (2) 2CO → C + CO2. The steady-state rate of reaction (1) increases in proportion to H2 pressure. On the other hand, reaction (2) is facilitated by the addition of an extremely small amount of H2, so that the rate becomes about eight times that for pure CO but hardly varies as more H2 is added. Similarly, there is a great difference in catalytic activity for ethylene hydrogenation between spent catalysts obtained in the deposition with and without H2. These findings suggest that hydrogen, even in a small amount, makes free Ni surface area larger than for pure CO.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00811358
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
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