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  • 1
    Electronic Resource
    Electronic Resource
    Schädelidentifizierung durch Superprojektion nach dem Verfahren der elektronischen Bildmischung, modifiziert zum Trickbild-Differenz-Verfahren (1977)
    Springer
    International journal of legal medicine 80 (1977), S. 189-190 
    Details
    ISSN: 1437-1596
    Keywords: Schädelidentifizierung, Video-Bildmischverfahren ; Video Bildmisch-verfahren, Schädelidentifizierung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Die Schädelidentifizierung nach dem Verfahren der elektronischen Bildmischung konnte mit Hilfe eines Video-Trickmischers über die reine Superprojektionsmethode hinaus zu einem Trickbild-Differenz-Verfahren weiter-entwickelt werden. Die Anwendung dieser Techniken in Kombination ist wegen der dadurch gegebenen verbesserten Kontrollmöglichkeit der Kongruenz des Superprojektionsmisch-bildes sehr zu empfehlen.
    Notes: Summary Skull identification by electronic photo-composition can, with the help of a video-animation compositor, be further developed beyond the pure superprojection technique into an animated picture-difference image. The employment of this combined technique is to be recommended on account of the improved possibilities of control to be realized in the congruity of the superprojection composite picture.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02114614
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  • 2
    Electronic Resource
    Electronic Resource
    Bactericidal Activity of Alveolar Macrophages is Suppressed by V-ATPase Inhibition (2000)
    Springer
    Lung 178 (2000), S. 91-104 
    Details
    ISSN: 1432-1750
    Keywords: Key words: Bafilomycin A1—Phagocytosis—Reactive oxygen species—Cytosolic pH.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Bafilomycin A1, a selective inhibitor of V-type H+-translocating ATPase (V-ATPase), may be a useful adjunct in cancer chemotherapy (Altan et al. [1998] J Exp Med 187:1583–1598). Therapeutic uses of the enzyme inhibitor need to consider the agent's potential effects on normal (nontumor) cells. This study determined the effects of bafilomycin A1 on resident alveolar macrophages (mφ). Treatment of alveolar mφ with bafilomycin A1 (10 μM, 1 h) caused a significant decrement in cytosolic pH. This was accompanied by marked alteration of mφ bactericidal capabilities. The enzyme inhibitor caused a marginal reduction in the phagocytosis of opsonized Staphylococcus aureus and significantly suppressed intracellular killing of the phagocytosed bacteria. In keeping with the effects on intracellular killing, bafilomycin A1 significantly reduced the production of reactive oxygen species (ROS). On the other hand, cell spreading was enhanced significantly by bafilomycin A1. Comparable changes in ROS generation and mφ spreading were produced by altering cytosolic pH through changes in extracellular pH (pHo) in the absence of bafilomycin A1. These findings suggest that the agent's effects on ROS production and mφ spreading were related to the accompanying changes in cytosolic pH. The enzyme inhibitor also altered mφ morphology, leading to the shortening of microvilli and focal loss of surface ruffles. These morphologic effects differed from those produced by altering cytosolic pH by changes in pHo. The results demonstrate that V-ATPase activity is an important determinant of mφ functioning and structure. Therapeutic use of V-ATPase inhibitors might be expected to compromise the bactericidal activity of alveolar mφ.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004080000012
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    Paper (German National Licenses)
    Fulltext
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