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  • Key words: Ruptured abdominal aortic aneurysm — Ischemic colitis — Flexible sigmoidoscopy  (1)
  • Mandelic and phenylglyoxylic acid excretion kinetics  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 61 (1988), S. 107-113 
    ISSN: 1432-1246
    Keywords: Mandelic and phenylglyoxylic acid excretion kinetics ; Styrene accumulation ; Styrene industrial exposure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The excretion kinetics of mandelic and phenylglyoxylic acids investigated over three subsequent days after cessation of styrene inhalation could be expressed by biphasic functions, similar for both metabolities; the half-times for the first and the second phases were 2.5 and 30 h, respectively. The possibility of styrene accumulation in exposure repeated daily was assessed by kinetic modelling; it appears negligible if measurements are based on urine samples collected at the end of the working shift. The above contention has been examined in workers exposed to styrene in the polyester industry: concentrations of styrene in air monitored continuously varied from 26 to 130 mg/m3. The relationship between styrene concentration and rate of urinary excretion of the total amount of mandelic and phenylglyoxylic acids was rectilinear and demonstrated a reasonable agreement between experimental and industrial data. The trends of concentrations within the day and week gave no indication of substantial styrene cumulation under repeated industrial exposure.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Surgical endoscopy and other interventional techniques 11 (1997), S. 113 -115 
    ISSN: 1432-2218
    Keywords: Key words: Ruptured abdominal aortic aneurysm — Ischemic colitis — Flexible sigmoidoscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: The development of colonic ischemia following repair of ruptured abdominal aortic aneurysm (AAA) is associated with significant morbidity and timely diagnosis is essential. The purpose of this study was to determine the efficacy of endoscopy in the diagnosis of colonic ischemia and in prediction of need for resection. Methods: Patients who underwent postoperative lower endoscopy after ruptured AAA from 1986 to 1995 were reviewed for endoscopic findings, clinical course, and patient outcome. Results: A total of 80 patients had ruptured AAA during the study period, of which 56 survived for longer than 24 h postoperatively. Flexible lower endoscopy was done in 18 patients (32%) on an average of 4.4 days following AAA repair (range 1–16). Indications for initial endoscopy included early or bloody stools in 12 (67%), hemodynamic instability or sepsis in eight (44%), and acidosis in four (22%). The extent of the examination was sigmoid or descending colon in 13, cecum in four, and transverse colon in one. Endoscopic findings were normal in four patients. Five examinations showed only areas of hemorrhagic mucosa. Absence of full-thickness ischemia was confirmed by clinical course or autopsy in these nine patients. Two examinations demonstrated full-thickness necrosis which was confirmed at subsequent laparotomy. In six examinations, ischemia was noted but judged to be limited to mucosa only. Absence of full-thickness disease was demonstrated by laparotomy in three and subsequent course in three. Eight patients (57%) with initial abnormal examinations underwent repeat endoscopy showing improved interval appearance in seven cases and progression to full-thickness ischemia in one patient. Conclusions: Flexible sigmoidoscopy reliably predicts full-thickness colonic ischemia following repair of ruptured aortic aneurysms. Patients with non-confluent ischemia limited to the mucosa can be safely followed by serial endoscopic examinations.
    Type of Medium: Electronic Resource
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