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  • 1
    Electronic Resource
    Electronic Resource
    Starvation in yeast increases non-adaptive mutation (1999)
    Springer
    Current genetics 35 (1999), S. 77-81 
    Details
    ISSN: 1432-0983
    Keywords: Key words Adaptive mutations ; 6-N-hydroxylaminopurine ; Saccharomyces cerevisiae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The frequency of reversion in a histidine-requiring mutant of Saccharomyces cerevisiae increases about ten-fold in stationary cells during histidine starvation. Histidine starvation enhances a similar frequency of reversion in a tryptophan-requiring mutant. Starvation, therefore, enhances mutation frequencies in a non-adaptive manner. The base analogue 6-N-hydroxylaminopurine (HAP) added prior to plating on medium with limited histidine strongly increases reversion of the histidine mutant. HAP-induced reversion increases further in stationary starving cells with the same kinetics as that which increases spontaneous reversion. Adding HAP to the stationary starving cells does not produce any effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002940050435
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Prevalence of polycystic ovaries in women with acne (1989)
    Springer
    Archives of dermatological research 281 (1989), S. 502-503 
    Details
    ISSN: 1432-069X
    Keywords: Acne ; Polycystic ovaries ; Pelvic ultrasound
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The prevalence of polycystic ovaries was determined by pelvic ultrasound imaging in 119 women (mean age, 23.6±6.06 years; range, 14–45 years) with acne but with no menstrual disorders, obesity, or hirsutism, and in 35 healthy controls (mean age, 25±5.8 years; range, 21–40 years). Polycystic ovaries were found in 54 out of 119 patients with acne (45.37%) and in 6 out of 35 controls (17.14%). The results of this study indicate that polycystic ovaries are common in women with acne and not necessarily associated with menstrual disorders, obesity, or hirsutism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00510088
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    Paper (German National Licenses)
    Fulltext
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