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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 44 (1982), S. 271-274 
    ISSN: 1432-0584
    Keywords: ALL ; Chromosome analysis ; Translocation t (4; 11)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two patients with acute lymphocytic leukemia are described in whom G- and R-banding analysis revealed in bone marrow cells a translocation t (4; 11) (q21; q23). The clinical data are compared to the other four cases with t (4; 11) reported so far in the literature. The anomaly seems to be characteristic for ALL. In addition it appears to be associated with a very high number of circumlating blasts and other poor prognostic factors.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 124 (1998), S. 199-206 
    ISSN: 1432-1335
    Keywords: Key words Soft-tissue sarcoma ; Survival ; Prognostic data
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Since 1988, treatment strategies for our sarcoma patients have been determined by the same team and operations performed by one surgeon. The aim of this study was to analyse prognostic data on local recurrence and survival of 101 consecutive patients who presented in our institution with the primary tumour manifestation. After a median follow-up of 35 months, the local recurrence rate was 13.5%, the mean survival time was 68 months and the 5-year survival rate was 83%. Besides positive lymph nodes (only 3 patients) the quality of resection significantly influenced local recurrences (P〈0.05). Univariate predictors of mortality were tumour grade (P〈0.01), tumour size (P〈0.05), distant metastases (P〈0.01), and resection quality (P〈0.01). Multivariate predictors of mortality consisted of grade (P〈0.0001), positive lymph nodes (P〈0.001) and resection quality (P〈0.01). In this homogeneous group of patients, excellent recurrence and survival rates could be achieved. An optimized surgical treatment not only reduces the rate of local recurrences but also augments survival time.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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