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Digitale Medien

Argyrophilic nucleolar organizer region counts in squamous cell carcinomas of the head and neck after irradiation and chemotherapy (1998)

Hammer, D. S. ; Herberhold, C. ; Pfeifer, U.

Springer

European archives of oto-rhino-laryngology and head & neck 255 (1998), S. 74-76

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Details

ISSN: 1434-4726

Schlagwort(e): Key words Squamous cell carcinoma ; Nucleolar ; organizer region ; Radiotherapy ; Chemotherapy

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract After irradiation or chemotherapy of tumors of the head and neck, histological alterations might be difficult to assess. In 30 cases of squamous cell carcinomas of the pharynx, changes in argyrophilic nucleolar organizer region (AgNOR) counts were investigated after therapy. After treatment a significant decrease of AgNOR counts was detected (P 〈 0.001). No significant differences could be found between groups treated with radiotherapy, chemotherapy or a combination of radiotherapy and chemotherapy. These findings suggest that AgNOR counts might be useful to assess cytotoxic effects on a subcellular level.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/s004050050022

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