ISSN:
1573-6903
Keywords:
LA-N-1 and LA-N-2 cells
;
human neuroblastoma clones
;
retinoic acid
;
ethanol
;
ethanolamine methylation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The sequential methylation of ethanolamine (Etn) or phosphorylethanolamine to the corresponding choline (Cho) derivatives was studied in both undifferentiated and retinoic acid (RA) differentiated human neuroblastoma clones LA-N-1 and LA-N-2. Conversion of Etn derivatives to the respective Cho metabolites was low in both cell types. However, after treatment of the cultures with ethanol or RA, the methylation of phosphoryl-Etn was stimulated while that of phosphatidyl-Etn was severely reduced in both cholinergic LA-N-2 and catecholaminergic LA-N-1 cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00967324
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