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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Urological research 12 (1984), S. 171-174 
    ISSN: 1434-0879
    Schlagwort(e): Testicular biopsy ; Cryptorchidism ; Fertility ; FSH ; LH ; T ; Estradiol
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary This prospective study conducted on 24 children, who have now reached adulthood, was undertaken to determine the value of testicular biopsies in cryptorchidism relative to fertility prognosis. A significant correlation between the number of germ cells in the biopsy and sperm count was found to exist (p〈5%). Thus, the testicular biopsy performed during orchiopexy was found to have a prognostic value. The hormonal findings (LH, FSH) suggest that in cryptorchid adults impaired Leyding cell function exists prognostic value with respect to fertility and the probability of discovering carcinoma in situ cells, it is strongly recommended that a testicular biopsy is performed in cryptorchid boys.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    European journal of pediatrics 146 (1987), S. S18 
    ISSN: 1432-1076
    Schlagwort(e): LH ; FSH ; Urine ; LH-RH
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The assay of urinary LH and FSH in first morning void urine can be used for the differential diagnosis between anorchism and bilateral cryptorchidism with impalpable testes. Furthermore, levels of urinary LH and FSH excretion and their response to intranasal stimulation with LH-RH prove helpful in the follow-up of patients under hormonal treatment, i.e. prolonged stimulation in hypogonadotrophic hypogonadism or suppression by an LH-RH analogue, for instance in precocious puberty. By increasing the sensitivity of the assay, the value of urinary gonadotrophins for the differential diagnosis and survey of hormonal treatment in very young children can be examined, and investigations of this kind are currently taking place. The method used obviously cannot assess the bioactivity of the excreted hormone, nor can it depict the pulsatility of gonadotrophin secretion.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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